The University of Applied Arts Vienna (‘the Angewandte’) has developed a bachelor’s and a master’s programme on socially responsibility, (in terms of the UN Agenda 2030) entrepreneurship education and complexity. The experience of the Angewandte is relevant to the HEInnovate community for at least three main reasons. First, it illustrates that entrepreneurship education encompasses a large domain of activities, fields and practices. Second, it shows that entrepreneurship education is relevant in all kinds of higher education institutions. Third, it demonstrates the increasing importance of entrepreneurial skills vis-à-vis the grand challenges of the next future, including social and environmental sustainability. This case study briefly discusses the evolution of entrepreneurship education at the Angewandte, and the important role the University of Applied Arts plays in the Vienna innovative ecosystem and far beyond.